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How The 'Pox' Epidemic Changed Vaccination Rules

During the 1898-1904 pox epidemic, public health officials and policemen forced thousands of Americans to be vaccinated against their will.

Historian Michael Willrich was planning to write a book about civil liberties in the aftermath of Sept. 11 when he stumbled across an article from The New York Times archives. It was about a 1901 smallpox vaccination raid in New York — when 250 men arrived at a Little Italy tenement house in the middle of the night and set about vaccinating everyone they could find.

"There were scenes of policemen holding down men in their night robes while vaccinators began their work on their arms," Willrich tells Fresh Air's Terry Gross. "Inspectors were going room to room looking for children with smallpox. And when they found them, they were literally tearing babes from their mothers' arms to take them to the city pesthouse [which housed smallpox victims.]"

The vaccination raid was not an isolated incident. As the smallpox epidemic swept across the country, New York and Boston policemen conducted several raids and health officials across the country ordered mandatory vaccinations in schools, factories and on railroads. In Pox: An American History, Willrich details how the smallpox epidemic of 1898-1904 had far-reaching implications for public health officials — as well as Americans concerned about their own civil liberties.

"110 years ago, vaccination was compelled by the state," he says. "But there no effort taken by the government to ensure that vaccines on the market were safe and effective. We live in a very different environment today where there are extensive regulations governing the entire vaccine industry."

At the turn of the 20th century, explains Willrich, there were little to no regulations governing the pharmaceutical industry. Many people were forced to receive the vaccine — most of the time against their will.

"There was one episode in Middlesboro, Ky., where the police and a group of vaccinators went into this African-American section of town, rounded up people outside this home, handcuffed the men and women and vaccinated them at gunpoint," says Willrich. "It's a shocking scene and very much at odds with our daily-held notions of American liberty."

People infected with small pox would also be quarantined against their will in large isolation hospitals called pest houses.

"People would literally dragged there against their will," he says. "Some of the most poignant scenes are when mothers are fighting with health officials to keep their children in their own homes rather than have them be taken off to a pesthouse. People at the time rightly associated pest houses with death. That's where someone was taken to die."